Head to Head
| MLB Exhibition | 2022/03/22 20:05 | SD Padres v CLE Guardians | W | 1-6 |
| MLB Spring Training | 2021/03/28 20:05 | SD Padres v CLE Guardians | D | 3-3 |
| MLB Spring Training | 2021/03/11 20:10 | CLE Guardians v SD Padres | L | 4-5 |
| MLB Exhibition | 2020/02/26 20:10 | CLE Guardians v SD Padres | L | 0-8 |
| MLB Spring Training | 2019/03/18 20:05 | SD Padres v CLE Guardians | L | 3-1 |
| MLB Spring Training | 2019/03/04 20:10 | CLE Guardians v SD Padres | L | 0-8 |
| MLB Spring Training | 2018/03/22 20:05 | SD Padres v CLE Guardians | L | 7-6 |
| MLB Spring Training | 2018/03/10 20:10 | CLE Guardians v SD Padres | D | 8-8 |
Home History
| MLB Exhibition | 2022/03/26 20:05 | OAK Athletics v CLE Guardians | W | 2-9 |
| MLB Spring Training | 2022/03/25 20:05 | CLE Guardians v SF Giants | W | 10-2 |
| MLB Exhibition | 2022/03/24 20:05 | SEA Mariners v CLE Guardians | L | 3-2 |
| MLB Exhibition | 2022/03/23 20:05 | CLE Guardians v LA Dodgers | L | 2-6 |
| MLB Exhibition | 2022/03/22 20:05 | SD Padres v CLE Guardians | W | 1-6 |
| MLB Exhibition | 2022/03/21 20:05 | TEX Rangers v CLE Guardians | L | 25-12 |
| MLB Exhibition | 2022/03/20 20:05 | CLE Guardians v OAK Athletics | D | 9-9 |
| MLB Spring Training | 2022/03/19 20:05 | CLE Guardians v CHI White Sox | W | 11-2 |
Away History
| MLB Exhibition | 2022/03/26 20:10 | CHI Cubs v SD Padres | D | 2-2 |
| MLB Exhibition | 2022/03/26 01:05 | SD Padres v LA Dodgers | D | 5-5 |
| MLB Exhibition | 2022/03/23 20:10 | LA Angels v SD Padres | W | 0-3 |
| MLB Exhibition | 2022/03/22 20:05 | SD Padres v CLE Guardians | L | 1-6 |
| MLB Exhibition | 2022/03/21 20:10 | COL Rockies v SD Padres | L | 8-4 |
| MLB Exhibition | 2022/03/20 20:10 | SD Padres v MIL Brewers | L | 3-6 |
| MLB Exhibition | 2022/03/19 20:05 | SD Padres v CHI Cubs | L | 4-5 |
| MLB Spring Training | 2022/03/18 20:10 | SEA Mariners v SD Padres | W | 4-6 |