[1] Cruz Azul 1-1 Santos Laguna [5] 2021-05-31 01:15
Stadium: Estadio Azteca Round: 1
Referee: Fernando Hernandez Gomez Home Manager: Armando Gonzalez Away Manager: Guillermo Almada
Head to Head
| Mexiko - Liga MX | 2021/05/28 02:00 | Santos Laguna v Cruz Azul | W | 0-1 |
| Mexiko - Liga MX | 2021/01/11 01:06 | Santos Laguna v Cruz Azul | L | 1-0 |
| Mexiko - Liga MX | 2020/07/26 02:00 | Cruz Azul v Santos Laguna | W | 2-0 |
| Mexiko - Liga MX | 2020/01/25 23:00 | Cruz Azul v Santos Laguna | W | 3-0 |
| Mexiko - Liga MX | 2019/11/11 00:45 | Santos Laguna v Cruz Azul | L | 3-1 |
| Mexiko - Liga MX | 2019/02/16 23:00 | Cruz Azul v Santos Laguna | L | 1-2 |
| Mexiko - Liga MX | 2018/08/26 23:00 | Santos Laguna v Cruz Azul | D | 1-1 |
| Mexiko - Liga MX | 2018/02/26 00:00 | Santos Laguna v Cruz Azul | L | 2-0 |
Home History
| Mexiko - Liga MX | 2021/05/28 02:00 | Santos Laguna v Cruz Azul | W | 0-1 |
| Mexiko - Liga MX | 2021/05/23 01:00 | Cruz Azul v Pachuca | W | 1-0 |
| Mexiko - Liga MX | 2021/05/20 01:30 | Pachuca v Cruz Azul | D | 0-0 |
| Mexiko - Liga MX | 2021/05/16 01:05 | Cruz Azul v Toluca | W | 3-1 |
| Mexiko - Liga MX | 2021/05/13 00:00 | Toluca v Cruz Azul | L | 2-1 |
| CONCACAF Champions Cup | 2021/05/05 02:15 | Cruz Azul v Toronto FC | W | 1-0 |
| Mexiko - Liga MX | 2021/05/02 00:00 | Cruz Azul v Tijuana | D | 1-1 |
| CONCACAF Champions Cup | 2021/04/28 02:00 | Toronto FC v Cruz Azul | W | 1-3 |
Away History
| Mexiko - Liga MX | 2021/05/28 02:00 | Santos Laguna v Cruz Azul | L | 0-1 |
| Mexiko - Liga MX | 2021/05/24 00:00 | Puebla v Santos Laguna | L | 1-0 |
| Mexiko - Liga MX | 2021/05/21 02:00 | Santos Laguna v Puebla | W | 3-0 |
| Mexiko - Liga MX | 2021/05/16 23:00 | Monterrey v Santos Laguna | D | 1-1 |
| Mexiko - Liga MX | 2021/05/14 02:05 | Santos Laguna v Monterrey | W | 2-1 |
| Mexiko - Liga MX | 2021/05/09 02:15 | Santos Laguna v Queretaro | W | 5-0 |
| Mexiko - Liga MX | 2021/05/03 00:06 | Santos Laguna v Puebla | D | 0-0 |
| Mexiko - Liga MX | 2021/04/27 02:00 | Pachuca v Santos Laguna | L | 1-0 |