[1] New England Revolution 0-1 Inter Miami CF [21] 2021-11-07 20:30
Stadium: Gillette Stadium
Referee: Alan Kelly Home Manager: Bruce Arena Away Manager: Phil Neville
Home History
| USA - MLS | 2021/10/27 23:00 | New England Revolution v Colorado Rapids | W | 1-0 |
| USA - MLS | 2021/10/24 23:30 | Orlando City SC v New England Revolution | D | 2-2 |
| USA - MLS | 2021/10/20 23:30 | DC United v New England Revolution | W | 2-3 |
| USA - MLS | 2021/10/16 23:00 | New England Revolution v Chicago Fire | D | 2-2 |
| USA - MLS | 2021/09/29 23:30 | CF Montreal v New England Revolution | W | 1-4 |
| USA - MLS | 2021/09/25 23:00 | New England Revolution v Orlando City SC | W | 2-1 |
| USA - MLS | 2021/09/23 00:00 | Chicago Fire v New England Revolution | W | 2-3 |
| USA - MLS | 2021/09/18 23:00 | New England Revolution v Columbus Crew | D | 1-1 |
Away History
| USA - MLS | 2021/10/30 17:30 | Inter Miami CF v New York City FC | L | 1-3 |
| USA - MLS | 2021/10/27 23:30 | Atlanta United v Inter Miami CF | L | 2-1 |
| USA - MLS | 2021/10/24 00:00 | Inter Miami CF v FC Cincinnati | W | 5-1 |
| USA - MLS | 2021/10/20 23:30 | Inter Miami CF v Toronto FC | W | 3-0 |
| USA - MLS | 2021/10/16 22:00 | Columbus Crew v Inter Miami CF | L | 4-0 |
| USA - MLS | 2021/10/09 22:00 | New York Red Bulls v Inter Miami CF | L | 1-0 |
| USA - MLS | 2021/10/03 21:30 | Portland Timbers v Inter Miami CF | L | 1-0 |
| USA - MLS | 2021/09/29 23:00 | Atlanta United v Inter Miami CF | L | 1-0 |