Home History
| NCAAF | 2000/11/04 12:00 | Florida State v Clemson | L | 54-7 |
| NCAAF | 2000/10/28 12:00 | Clemson v Georgia Tech | L | 28-31 |
| NCAAF | 2000/10/21 12:00 | North Carolina v Clemson | W | 24-38 |
| NCAAF | 2000/10/14 12:00 | Clemson v Maryland | W | 35-14 |
| NCAAF | 2000/10/07 12:00 | Clemson v NC State | W | 34-27 |
| NCAAF | 2000/09/30 12:00 | Duke v Clemson | W | 22-52 |
| NCAAF | 2000/09/23 12:00 | Virginia v Clemson | W | 10-31 |
| NCAAF | 2000/09/16 12:00 | Clemson v Wake Forest | W | 55-7 |
Away History
| NCAAF | 2000/11/11 12:00 | Florida v South Carolina | L | 41-21 |
| NCAAF | 2000/10/28 12:00 | South Carolina v Tennessee | L | 14-17 |
| NCAAF | 2000/10/21 12:00 | Vanderbilt v South Carolina | W | 14-30 |
| NCAAF | 2000/10/14 12:00 | South Carolina v Arkansas | W | 27-7 |
| NCAAF | 2000/10/07 12:00 | Kentucky v South Carolina | W | 17-20 |
| NCAAF | 2000/09/30 12:00 | Alabama v South Carolina | L | 27-17 |
| NCAAF | 2000/09/23 12:00 | South Carolina v Mississippi State | W | 23-19 |
| NCAAF | 2000/09/16 12:00 | South Carolina v Eastern Michigan | W | 41-6 |